GSK Scientific Leader Post Vacancy 2020 – Apply Online
GSK Scientific Leader Post. GSK’s Biopharm development platform is reliable and proven, with clear strengths in antibody discovery, formulation, analysis and drug substance manufacture. This success has led to increased investment in the Biopharm business, with the aim of delivering industry-leading Biopharm capabilities that will enable design for developability, improve biopharma quality and accelerate portfolio fill and flow.
Job Title: Scientific Leader
Location: USA – Pennsylvania – King of Prussia
Basic Qualifications:
GSK Scientific Leader Post
We are looking for professionals with these required skills to achieve our goals:
- PhD in Chemical/Biochemical Engineering, Biochemistry, Chemistry, or Biology, or other relevant disciplines with a minimum of 4 years industrial experience in therapeutic protein purification process development, or BS/MS graduate with equivalent experience.
- Expertise in therapeutic protein purification, process development, scale-up, and technology transfer.
- Thorough knowledge of drug development and of regulatory requirements in the industry, including experience with cGMPs.
- Experience contributing to CMC matrix project teams.
Preferred Qualifications:
GSK Scientific Leader Post
If you have the following characteristics, it would be a plus:
- Demonstrated record of achievement and broad integrated knowledge of all aspects of the work.
- Experience with both early- and late-phase development of purification processes, process scale-up, technology transfer (internal and to external CMO), process validation and BLA/MAA preparation for biopharmaceuticals.
- Previous experience demonstrating strong business acumen in supporting process development and manufacturing activities is strongly preferred.
- Requires excellent oral and written communication skills to effectively deliver portfolio programs.
- Broad and integrated knowledge and experience that can impact project and work-group direction.
- Demonstrated record of innovation and technology development. Knowledge of regulatory requirements for biopharmaceutical production, including principles of quality by design and virus clearance validation.
- GSK Scientific Leader Post Experience with the purification of protein products from both mammalian and microbial cell culture.
- Experience executing performance management cycle activities.
Experience leading CMC matrix project teams. - Involvement in the external scientific and industrial community as demonstrated by a track record of presentations, publications and participation in conferences.
- Demonstrated ability to supervise and mentor others. Experience recruiting and training staff.
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:
- As a scientific leader, use extensive technical knowledge and ability to turn concepts into manufacturing methods and integrated processes, interpreting complex data and information and making decisions and proposals that impact timelines, quality and cost.
- GSK Scientific Leader Post Set clearly defined goals and objectives, and guide your team in the design, execution and interpretation of protein purification experiments. Ensure well-organized, clear and complete documentation and data integrity of all activities across areas of responsibility.
- Manage across multiple projects simultaneously, leading matrix teams, where appropriate.
- Supervise, mentor, and train staff members (a group of approx. 3-8 scientists, engineers, and technicians).
- Apply engineering concepts, statistical analysis, and advanced data analytics to gain process understanding and improvement.
- Manage and maintain laboratory capabilities focused on downstream process scale-up, supporting and collaborating throughout the DPD department.
- Contribute to setting new technology strategy and guide the evaluation and integration of innovative purification technologies. Establish and maintain an understanding of current trends in purification technologies.
- Conduct process robustness, characterization, validation and technology transfer for commercial manufacture, as well as process transfers to support manufacture for early- and late-stage clinical trials.
- Involvement in the authorship and review of INDs/IMPDs and BLAs/MAAs for biopharmaceuticals;
