AstraZeneca Seeks In Vivo Scientist for Oncology Research – BS Biology Jobs
At AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.
About AstraZeneca
AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas – breast, ovarian, lung, and hematological cancers.
Position – In Vivo Scientist, Oncology Research
This Opportunity – BS Biology Jobs
We are seeking a highly motivated and independent Scientist in cancer pharmacology with a track record of scientific excellence in the area of in vivo cancer modeling, to join our In Vivo Pharmacology Team in Waltham, MA USA. As a Scientist, you will be a key member of a team focused on delivering all aspects of in vivo pharmacology support. You will bring your theoretical and practical expertise to establish assay systems and deliver datasets that will have a direct impact on the drug discovery process and pipeline.
Key Duties And Responsibilities
- Develop, design, conduct, and analyze in vivo experiments to assess the function of candidate oncology drugs and dissect the mechanism of action of novel cancer therapeutics.
- Support cross-functional teams and work collaboratively with project leaders to ensure timely generation and dissemination of critical program data.
- Contribute to scientific publication goals.
- Stay up to date with relevant technical and intellectual scientific expertise in tumor biology, pharmacology, and cancer modeling.
Essential Requirements
- B.S. in Biology, Pharmacology, or other related scientific discipline with 3-6 yrs. relevant scientific experience; M.S. – 2-5 yrs. MS desired but not required.
- Experience developing and working with complex in vivo models of cancer, such as cell line derived xenograft (solid and hematological tumors) patient derived xenograft (PDX), syngeneic and autochthonous mouse models.
- Experience delivering in vivo pharmacology studies in mouse tumor models, including dose-finding tolerability studies, PK/PD and efficacy studies.
- Experience with a range of in vitro skills, e.g. cell culture, molecular biology, immunoblotting, flow cytometry, and ELISA.
- Works independently, assesses and reports data in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery.
- Strong interpersonal and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment.
- Excellent communication and presentation skills.
Desirable Requirements – BS Biology Jobs
- Biotechnology or pharmaceutical industry experience preferred but not essential.
- Experience with orthotopic xenograft and humanized models of cancer.
- Experience using biologics including, peptides, antibodies, or antibody-drug conjugates.
- Knowledge of the pharmaceutical industry drug discovery process.
