RNAi Discovery Job at Alnylam Pharmaceuticals – Biology/ Biochemistry Candidates Apply Now!
Alnylam Pharmaceuticals is at the forefront of RNAi therapeutics, transforming groundbreaking science into real-world treatments. We are seeking a Scientist, RNAi Discovery to join our Research Analytics team in Cambridge, MA. This role focuses on advancing RNA interference (RNAi) research through cutting-edge analytical methods, enhancing siRNA therapeutics, and collaborating with cross-functional teams. If you’re passionate about pioneering the future of medicine, explore this exciting opportunity at
Alnylam.Job Posting: Scientist, RNAi Discovery
Location: United States, Cambridge, MA, USA
Overview
The Research Organization at Alnylam is looking to appoint a Scientist within the Research Analytics team. This role, part of the RNAi discovery group, will be instrumental in advancing the understanding of RNAi therapeutics. Our Research Analytics team is dedicated to deepening insights into siRNA and siRNA-conjugates through a comprehensive analytical framework.
Key Responsibilities
- Design and conduct in vivo and in vitro studies to assess the activity, stability, and distribution of siRNAs and siRNA-conjugates.
- Identify and evaluate new analytical methods to enhance the sensitivity and detection capabilities of siRNA treatments.
- Assist in establishing a versatile analytical lab to facilitate expansion into novel chemical domains.
- Collaborate with the Early Development team to optimize DMPK techniques and ensure seamless method transfer.
- Participate in cross-functional meetings and communicate vital information to Research & Development stakeholders.
- Effectively communicate results to key internal teams.
Qualifications
- Ph.D. (0-3 years), Masters (3-6 years), or BS (7-10 years) in chemistry, biology, biochemistry, or related fields.
- Proficiency in working with LCMS Instrumentation and optimizing LCMS methods for complex biological inquiries.
- Broad experience in various analytical techniques, including HPLC, MS, PAGE, WB, and more.
- Deep knowledge of oligonucleotide therapeutics or peptide/protein therapeutics with a focus on analytics.
- Strong teamwork and communication skills with a focus on collaboration and attention to detail.
Keywords: Alnylam, RNAi therapeutics, Scientist, Research Analytics, RNAi discovery, siRNA, DMPK methods
